Publications

2019

• Y Zhu, T Saif, FW DelRio. Recent Advances in Micro, Nano, and Cell Mechanics. Experimental Mechanics 59 (3), 277-278, 2019.

• Zhengwei Li, Yongbeom Seo, Onur Aydin, Mohamed Elhebeary, Roger D. Kamm, Hyunjoon Kong, and M. Taher A. Saif. A biohybrid valveless pump-bot powered by engineered skeletal muscle. Proceedings of the National Academy of Science, USA January 29, 2019 116 (5) 1543-1548.

• Andrew W Holle, Neethu Govindan Kutty Devi, Kim Clar, Anthony Fan, Taher Saif, Ralf Kemkemer, Joachim P Spatz. Cancer cells invade confined microchannels via a self-directed mesenchymal-to-amoeboid transition. Nano Letters, 19 (4), 2280-2290, 2019, DOI: 1021/acs.nanolett.8b04720.

• J. Williams and M. T. A. Saif. Phase dependent mechanosensitivity in cardiomyocytes. Journal of Experimental Mechanics. Experimental Mechanics, 59 (3), 387-393, 2019, https://doi.org/10.1007/s11340-019-00472-9

• Mohamed Elhebeary, Md Abul Bashar Emon, Onur Aydin and  M. Taher A. Saif. A novel technique for in situ uniaxial tests of self-assembled soft biomaterials. Lab Chip, 2019,19 (7), 1153-1161 https://doi.org/10.1039/C8LC01273C.

• Mikhail E. Kandel, Wenlong Lu, Jon Liang, Onur Aydin, Taher A. Saif and Gabriel Popescu. Cell-to-cell influence on growth in large Biomedical Optics Express, Vol. 10, No. 9 / 1 September 2019.

• William C. Ballance, Inkyu Oh, Yang Lai, Mohamed Elhebeary, Taher Saif, Yuhang Hu and Hyunjoon Kong Vibration at structural resonance frequency of hydrophilic substrates enhances biofilm removal. Sensors and Actuators B: Chemical, Volume 299, 15 November 2019, 126950 org/10.1016/j.snb.2019.126950

• Anthony Fan, Saddam Hossain Joy and and Taher Saif. A connected cytoskeleton network generates axonal tension in embryonic Drosophila. Lab on a Chip (in press)

• Zhang, Yao; Shi, Xuechen; Zhao, Tiankai; Huang, Changjin; Wei, Qiong; Tang, Xin; Santy, Lorraine; Saif, Taher; Zhang, Sulin. A Traction Force Threshold Signifies Metastatic Phenotypic Change in Multicellular Epithelia. Soft Matter (revised submission in review).

• Jesica Bauer, Bashar Emon, Georgina Mancinelli, Alexandra L Thomas, Jonas J Staudacher, Nancy Krett, M Taher Saif, and Barbara Jung. Increased stiffness of the tumor microenvironment in colon cancer stimulates cancer associated fibroblast-mediated prometastatic activin signaling. Scientific Reports (revised submission in review).

• Onur Aydin, Austin P. Passaro, Mohamed Elhebeary, Gelson J. Pagan-Diaz, Anthony Fan, Sittinon Nuethong, Rashid Bashir, Steven L. Stice and M. Taher A. Saif. 3D co-culture platform reveals functional outcomes of crosstalk between neural networks and muscles in early in vitro Lab on a Chip –(revised submission in Review).

• Aydin, X. Zhang, G. Pagan-Diaz, S. Nuethong, R. Bashir, M. Gazzola, T. Saif. (2019) Biohybrid motile bots with neuronal control. Proceedings of the National Academy of Sciences(in press).

2018

• Fan A, Tofangchi A, De Venecia M, Saif MT. A simple microfluidic platform for partial treatment of insuspendable tissue samples with orientation control. Lab Chip, 2018, 18 (5), 735-742. DOI:10.1039/C7LC00984D

• Roger D. Kamm, Rashid Bashir, Natasha Arora, Roy D. Dar, Linda G. Griffith, Melissa L. Kemp, Kathy Kinlaw, Michael Levin, Adam C. Martin, Todd C. McDevitt, Robert M. Nerem, Mark Powers, Taher A. Saif, Shuichi Takayama, Shoji Takeuchi, Ron Weiss, Kaiming Ye, Hannah G. Yevick, Muhammad Zaman. Perspective: The Promise of Multi-cellular Engineered Living Systems. APL Bioengineering 2, 040901 (2018)

• Danielle Posey, Paris Blaisdell-Pijuan, Samantha K. Knoll, Taher A. Saif, and Wylie W. Ahmed. Small-scale displacement fluctuations of vesicles in Scientific Reports 2018, 13294 10.1038/s41598-018-31656-3.

• Gelson J. Pagan-Diaz, Xiaotian Zhang, Lauren Grant, Yongdeok Kim, Onur Aydin, Caroline Cvetkovic, Eukyung Ko, Hyunjoon Kong, Taher Saif, Mattia Gazzola, Rashid Bashir. Simulation and fabrication of stronger, larger and faster walking biohybrid machines. Advanced Functional Materials, Vol 28, Issue 23, published online Aug 13, 2018, org/10.1002/adfm.201801145

• Jan-Kai Chang, Emon Bashar, Chia-Shuo Li, Quansan Yang, Hui-Ping Chang, Zijian Yang, Chih-I Wu, Taher A. Saif, and John A. Rogers. Cytotoxicity and in vitro Degradation Kinetics of Foundry-Compatible Semiconductor Nanomembranes and Electronic Microcomponents. ACS Nano, 12 (10), 9721-9732, 2018, DOI:10.1021/acsnano.8b04513.

• Mohamed Elhebeary, and M. Taher A. Saif. A novel MEMS stage for in-situ thermomechanical testing of single crystal silicon microbeams under bending. Extreme Mechanics Letter, Volume 23, September 2018, Pages 1-8, org/10.1016/j.eml.2018.06.009

• Emon Bashar, Jessica Bauer, Yasna Jain, Barbara Jung and Taher Saif. Biophysics of Tumor Microenvironment and cancer metastasis – a mini review. Computational and Structural Biotechnology Journal, 16 (2018) 279–287.

2017

• Mohamed Elhebeary and M T A Saif. “Design, Simulation, and Testing of a Novel Bending Stage for Mechanical Characterization of Materials”, Experimental Mechanics, 2017;57:89. doi:10.1007/s11340-016-0195-5

• Mohamed Elhebeary and M T A Saif. “Lessons learned from nanoscale specimens tested by MEMS based apparatus”, Journal of Physics D: Applied Physics, 50 (2017) 243001.

• Fan A, Tofangchi A, Kandel M, Popescu G, Saif T. Coupled circumferential and axial tension driven by actin and myosin influences in vivo axon diameter. Scientific Reports, 2017 Oct 27;7(1):14188. doi: 10.1038/s41598-017-13830-1. PMID:29079766, PMCID:PMC5660205.

Holle AW, Young JL, Van Vliet KJ, Kamm RD, Discher DE, Janmey PA, Spatz JP, Saif MT. Cell-ECM mechanobiology- forceful tools and emerging needs for basic and translational research. Nano Letters 2018, Jan 10;18(1):1-8. doi: 10.1021/acs.nanolett.7b04982. Epub 2017 Dec 6.

2016

• Samantha Knoll and M T A Saif. Light induced localized and abrupt force relaxations in fibroblasts on soft substrates. Extreme Mechanics Letters http://dx.doi.org/10.1016/j.eml.2016.03.009 (2016)

• Ali Tofangchi A*, Anthony Fan* and M T A Saif. Mechanism of Axonal Contractility in Embryonic Drosophila Motor Neurons In Vivo. Biophysical Journal. 2016 Oct 4;111(7):1519-1527. doi: 10.1016/j.bpj.2016.08.024. [Cover article] [Cover image] [Biophysics Society blog], PubMed ID: 27705774

• Junmin Lee, Amr A. Abdeen, Xin Tang, Taher A. Saif, and Kristopher A. Kilian, Matrix directed adipogenesis and neurogenesis of mesenchymal stem cells derived from adipose tissue and bone marrow, Acta Biomaterialia, 2016, 42, 46-55

2015

• Ali, M. Yakut, Anand, S. V., Tangella, K., Ramkumar, D., and Saif, M. Taher A. Isolation of Primary Human Colon Tumor Cells from Surgical Tissues and Culturing them Directly on Soft Elastic Substrates for Traction Cytometry. Journal of Visualized Experiments, 2015 Jun 4;(100):e52532. doi: 10.3791/52532.

• Sandeep Anand, M Yakut Ali and M Taher A Saif. Cell culture on microfabricated one-dimensional polymeric structures for bio-actuator and bio-bot applications. Lab Chip, 2015, Advance Article, published online 17 Feb 2015, DOI: 1039/C4LC01471E

• Samantha Knoll, Wylie Ahmed, and Taher Saif. Contractile dynamics change before morphological cues during fluorescence illumination. Scientific Reports 5, Article number: 18513 (2015). doi:10.1038/srep18513

• Slater, Bernard J, Fan, Anthony Y., Stebbings, Kevin A, Saif, M Taher A and Llano, Daniel A. Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging. Journal of Visualized Experiments (103), e53067, doi:10.3791/53067 (2015)

• Mohamed Elhebeary and M Taher A Saif. A Micromechanical Bending Stage for Studying Mechanical Properties of Materials Using Nanoindenter. Appl. Mech 82(12), 121004 (2015) doi: 10.1115/1.4031334.

• Anthony Fan, Kevin Stebbings, Daniel Llano, and Taher Saif Stretch Induced Hyperexcitibility of Mice Callosal Pathway, Front Cell Neurosci. 2015 Aug 5;9:292. doi:10.3389/fncel.2015.00292. eCollection 2015, PMID:26300729

• Junmin Lee, Amr A. Abdeen, Xin Tang, Taher A. Saif, and Kristopher A. Kilian. Geometric guidance of integrin mediated traction stress during stem cell differentiation. Biomaterials, Volume 69, November 2015, Pages 174–183.

• Mayandi Sivaguru, Glenn Fried, Barghav S. Sivaguru, Vignesh A. Sivaguru, Xiaochen Lu, Kyung Hwa Choi, M Taher A Saif, Brian Lin and Sakthivel Sadayappan. Cardiac muscle organization revealed in 3-D by imaging whole-mount mouse hearts using two-photon fluorescence and confocal microscopy. BioTechniques, Vol. 59, No. 5, November 2015, pp. 295–308.

• Sandeep V. Anand and M. Taher A. Saif. Emergent dynamics of cardiomyocyte clusters on deformable polymeric substrates. Extreme Mechanics Letters, doi:10.1016/j.eml.2015.09.008 (2015).

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Book Chapters

      • Nanotechnology, MacDonald, N. C., Saif, M. T. A., Millar, S. The Industrial Electronics Handbook, Editor-in-Chief J. David Irwin, CRC Press, pp 1500-1505, 1997.
      • Mechanical Testing at the Micro/Nano Scale, Haque, A., Saif, M. T. A. Springer Handbook of Experimental Solid Mechanics, Editor –in-Chief W. N. Sharpe, Jr.